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Pediatrics May 17, 2010

Ample evidence suggests that an imbalance in dopaminergic tone impacts the expression levels of neuropeptides like somatostatin (SST) and neuropeptide Y (NPY), as seen in patients with Parkinsons disease and HD as well as in rodent models 15,16,17,18

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We tested this hypothesis by injecting Cre-dependent Gsto2 -short hairpin RNA (shRNA) or a scrambled-shRNA viral construct in the striatum of Trkb Penk -KO mice to allow expression of the shRNA specifically in enkephalinergic neurons at 3 months (Fig

(2015) Neuroinflammation in temporal lobe epilepsy measured using positron emission tomographic imaging of translocator protein

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